Holy One of Jacob is a name of God that only occurs once, in the Old Testament. More common is the name Holy One of Israel, or simply, Holy One.
God is holy. These names tell us that but also remind us of His relationship with individuals like Jacob (whose name changed to Israel) and with whole groups of people, like the nation of Israel.
The word “holy” means set apart.
Holy One of Jacob in Hebrew:
Strong’s Concordance numbers: 6918, 3290
Bible reference: Isa. 29:23
When they see among them their children,
the work of my hands,
they will keep my name holy;
they will acknowledge the holiness of the Holy One of Jacob,
and will stand in awe of the God of Israel. (Isa. 29:23 NIV)
Jesus is called the Holy One of God. The name Holy One is common throughout the Bible.